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221 Main - Restaurant & Cocktail House
Our Story
Welcome to 221 Main - Restaurant & Cocktail House, an award-winning steakhouse located in the heart of St. Joseph, Michigan. Since 2012, we have been dedicated to providing an unforgettable dining experience with a menu that celebrates exceptional flavor and quality. We pride ourselves on offering a diverse range of dishes, all crafted from the finest ingredients.
At 221 Main, we specialize in steaks. Our offerings include classic cuts like ribeye and filet mignon, available daily to ensure every visit feels like a special occasion. For those seeking something unique, our signature Surf-n-Turf and BC Ribeye, seasoned to perfection, are standout dishes that elevate your dining experience. Each bite reflects our commitment to quality and flavor, making our steaks a memorable part of your visit.
Seafood enthusiasts will appreciate our fresh Atlantic Salmon and Perch, which capture the essence of coastal cuisine. Other popular dishes include Chicken Marsala, creamy Mac & Cheese, and our flavorful Seafood Pasta—each one crafted with care to satisfy every palate. Whether it’s a casual dinner or a special celebration, 221 Main offers a menu sure to delight.
Our vibrant bar scene is the perfect complement to our food. Enjoy hand-crafted cocktails expertly mixed to enhance your meal, or choose from a selection of local craft beers and global wines. With something for every taste, we ensure that your drink experience is as enjoyable as your meal.
221 Main is also an ideal venue for private events, offering event space rentals for gatherings of all sizes. Our catering services allow you to bring the 221 Main experience to your own location, while private dining options offer a personalized touch for your special occasions. We also offer convenient takeout services, so you can enjoy our cuisine wherever you are.
What truly sets 221 Main apart is our commitment to hospitality. From the moment you walk in, our attentive staff ensures that your dining experience exceeds expectations. Join us at 221 Main - Restaurant & Cocktail House and discover why we’ve become a beloved dining destination in St. Joseph!
Areas Served
Berrien County, MI | Cass County, MI | Van Buren County, MI | Allegan County, MI | Kalamazoo County, MI | Kent County, MI | Lake County, IN | St. Joseph, MI | St. Joseph County, IN
What We Offer
Our Specialties include:
- Award Winning Steakhouse and Cocktail Lounge
- The Terrace
- Copper Pot Breakfast Cafe
- The Largest Whiskey In The State
- 335 Whiskeys From Around The World
- Delicious Seafood
- Parmesan Encrusted Whitefish
- Child-Friendly
- Gluten-Free Options
Our Services include:
- Weddings
- Rehearsal Dinners
- Private Dining
- Event Catering
- Takeout
- Customizable Event Menus
- Bar Service
- Event Space Rental
- Outdoor seating
- Waitlist Management
- Catering
- Seasonal Menus
- Event Hosting
- Corporate Catering
- Coffee Bar
- Sustainable Packages
- Online Reservations
- Brunch
- Breakfast
Our Products include:
- Surf and Turf
- Filet Mignon
- Shrimp
- Garlic Ribeye
- Steak Fries
- Roasted Whitefish
- Blackened Salmon
- Lake Perch
- Seafood Pasta
- Short Ribs
- Sirloin
- Steakhouse Burgers
- Chicken Marsala
- Eggs Benedict
- Bloody Marys
- Wines
- Draft Beers
- Craft Cocktails
- Champagne
- Prosecco
Testimonials
On 1/9/2025
Greg Parrett
had this to say:
I considered 221 Main one of the top three fine dining restaurants in the St Joseph area. Robert Montgomery runs a first class establishment can I have never had anything less than a five-star experience. Their steaks and prime rib are prepared exactly the way their ordered and their seafood always tastes fresh.
I highly recommend 221 Main as a place to go for a fine dining experience
On 1/4/2025
Chris Bates
had this to say:
Fantastic place for a rehearsal dinner. Owner and staff were great from start to finish
On 12/28/2024
Lisa Ichniowski
had this to say:
Best Restaurant in Saint Joseph by far. The food, drinks, atmosphere, and service are AMAZING! The owner always checks in to ask about your experience.
On 12/26/2024
Julie K.
had this to say:
Cute, cozy, and delicious, 221 Main has it all!
Impromptu early birthday dinner led us to dine here. When we were first asked for a reservation, I was nervous they were booked, or one of "those places" but the owner was warm and gracious. That definitely set the tone for the evening!
The seasonal decor was just perfect, I'd dine here constantly for the holidays!
Though we didn't love the dressing of the Caesar salad (too fishy?) everything else was 10/10. I'm usually not a fan of perch, but this is the best perch I've ever tried! The lemon butter blanc was *chef's kiss* absolutely delectable. My husband's sirloin was sooooo tender and perfectly cooked. The accompanying vegetables were also great!
The pearnaked lady cocktail was worth ordering. Our server was also the bartender there, and she knew exactly what we'd want!
221 Main is a special place worth dining at time and time again!
On 12/21/2024
Joseph Keefe
had this to say:
Great food. Wonderful service. Excellent people. It's our regular dessert and drinks stop.
Contact Us
221 Main - Restaurant & Cocktail House
221 Main St St joseph, MI 49085
Phone: (269) 982-4000
Email: 221reservations
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Payment Types Accepted
Visa, MasterCard, Discover, American Express, Apple Pay, Android Pay, Debit Cards, Cash
Our Hours
Holiday Hours May Vary. Please Call For Details.
Thursday: 5:00 PM - 9:00 PM
Friday: 5:00 PM - 9:00 PM
Saturday: 5:00 PM - 9:00 PM
Sunday: 5:00 PM - 9:00 PM
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